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Resveratrol Potentiates Glucose-stimulated Insulin Secretion in INS-1E β-Cells and Human Islets through a SIRT1-dependent Mechanism

Resveratrol, a polyphenol compound, is known for its effects on energy homeostasis. With properties of energy sensors mediating effects of calorie restriction, sirtuins are targets of resveratrol. The mammalian sirtuin homolog SIRT1 is a protein deacetylase playing a role in glucose metabolism and i...

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Detalhes bibliográficos
Main Authors: Vetterli, Laurène, Brun, Thierry, Giovannoni, Laurianne, Bosco, Domenico, Maechler, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057791/
https://ncbi.nlm.nih.gov/pubmed/21163946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.176842
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