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Active Immunotherapy Induces Antibody Responses that Target Tumor Angiogenesis

The inhibition of vascular endothelial growth factor (VEGF) signaling with antibodies or small molecules achieves clinical benefits in diverse solid malignancies. Nonetheless, therapeutic effects are usually not sustained, and most patients eventually succumb to progressive disease, indicating that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schoenfeld, Jonathan, Jinushi, Masahisa, Nakazaki, Yukoh, Wiener, Daniel, Park, Joosang, Soiffer, Robert, Neuberg, Donna, Mihm, Martin, Hodi, F. Stephen, Dranoff, Glenn
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057563/
https://ncbi.nlm.nih.gov/pubmed/21159637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1852
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