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Acquired resistance to MET kinase inhibition in MET-dependent non-small cell lung cancer cells mediated by a switch to EGFR dependency
The MET receptor tyrosine kinase has been implicated in several solid tumor settings, with MET gene amplification present in a subset of patients with epithelial tumors, including non-small cell lung cancer (NSCLC). MET gene amplification also appears to underlie acquired resistance to EGFR kinase i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057521/ https://ncbi.nlm.nih.gov/pubmed/20124471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3620 |
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