Acquired resistance to MET kinase inhibition in MET-dependent non-small cell lung cancer cells mediated by a switch to EGFR dependency

The MET receptor tyrosine kinase has been implicated in several solid tumor settings, with MET gene amplification present in a subset of patients with epithelial tumors, including non-small cell lung cancer (NSCLC). MET gene amplification also appears to underlie acquired resistance to EGFR kinase i...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: McDermott, Ultan, Pusapati, Raju V., Christensen, James G., Gray, Nathanael S., Settleman, Jeff
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057521/
https://ncbi.nlm.nih.gov/pubmed/20124471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3620
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares