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Selective Targeting of Human Alloresponsive CD8(+) Effector Memory T Cells Based on CD2 Expression
Costimulation blockade, specifically CD28/B7 inhibition with belatacept, is an emerging clinical replacement for calcineurin inhibitor-based immunosuppression in allotransplantation. However, there is accumulating evidence that belatacept incompletely controls alloreactive T cells that lose CD28 exp...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057516/ https://ncbi.nlm.nih.gov/pubmed/21070604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2010.03317.x |
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