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Selective Targeting of Human Alloresponsive CD8(+) Effector Memory T Cells Based on CD2 Expression

Costimulation blockade, specifically CD28/B7 inhibition with belatacept, is an emerging clinical replacement for calcineurin inhibitor-based immunosuppression in allotransplantation. However, there is accumulating evidence that belatacept incompletely controls alloreactive T cells that lose CD28 exp...

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Detalhes bibliográficos
Main Authors: Lo, D.J., Weaver, T. A., Stempora, L., Mehta, A. K., Ford, M. L., Larsen, C. P., Kirk, A. D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057516/
https://ncbi.nlm.nih.gov/pubmed/21070604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2010.03317.x
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