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A Common Connexin-40 Gene Promoter Variant Affects Connexin-40 Expression in Human Atria and Is Associated with Atrial Fibrillation

BACKGROUND: A common single-nucleotide polymorphism (SNP) in the promoter of the Connexin-40 (Cx40) gene GJA5 was suggested to affect Cx40 promoter activity and the risk of atrial fibrillation (AF), but the role of other common Cx40 polymorphisms is unknown. METHODS AND RESULTS: 8 SNPs within the Cx...

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Detalhes bibliográficos
Main Authors: Wirka, Robert C, Gore, Shamone, Van Wagoner, David R., Arking, Dan E., Lubitz, Steven A., Lunetta, Kathryn L., Benjamin, Emelia J., Alonso, Alvaro, Ellinor, Patrick T., Barnard, John, Chung, Mina K., Smith, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057452/
https://ncbi.nlm.nih.gov/pubmed/21076161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.110.959726
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