A Common Connexin-40 Gene Promoter Variant Affects Connexin-40 Expression in Human Atria and Is Associated with Atrial Fibrillation

BACKGROUND: A common single-nucleotide polymorphism (SNP) in the promoter of the Connexin-40 (Cx40) gene GJA5 was suggested to affect Cx40 promoter activity and the risk of atrial fibrillation (AF), but the role of other common Cx40 polymorphisms is unknown. METHODS AND RESULTS: 8 SNPs within the Cx...

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Bibliografiske detaljer
Main Authors: Wirka, Robert C, Gore, Shamone, Van Wagoner, David R., Arking, Dan E., Lubitz, Steven A., Lunetta, Kathryn L., Benjamin, Emelia J., Alonso, Alvaro, Ellinor, Patrick T., Barnard, John, Chung, Mina K., Smith, Jonathan D.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057452/
https://ncbi.nlm.nih.gov/pubmed/21076161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.110.959726
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