A Common Connexin-40 Gene Promoter Variant Affects Connexin-40 Expression in Human Atria and Is Associated with Atrial Fibrillation

BACKGROUND: A common single-nucleotide polymorphism (SNP) in the promoter of the Connexin-40 (Cx40) gene GJA5 was suggested to affect Cx40 promoter activity and the risk of atrial fibrillation (AF), but the role of other common Cx40 polymorphisms is unknown. METHODS AND RESULTS: 8 SNPs within the Cx...

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主要な著者: Wirka, Robert C, Gore, Shamone, Van Wagoner, David R., Arking, Dan E., Lubitz, Steven A., Lunetta, Kathryn L., Benjamin, Emelia J., Alonso, Alvaro, Ellinor, Patrick T., Barnard, John, Chung, Mina K., Smith, Jonathan D.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057452/
https://ncbi.nlm.nih.gov/pubmed/21076161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.110.959726
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