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Brain penetrating IgG-erythropoietin fusion protein is neuroprotective following intravenous treatment in Parkinson's disease in the mouse

Parkinson's disease (PD) is caused by oxidative stress, and erythropoietin (EPO) reduces oxidative stress in the brain. However, EPO cannot be developed as a treatment for PD, because EPO does not cross the blood-brain barrier (BBB). A brain-penetrating form of human EPO has been developed wher...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zhou, Qing-Hui, Hui, Eric Ka-Wai, Lu, Jeff Zhiqiang, Boado, Ruben J., Pardridge, William M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057388/
https://ncbi.nlm.nih.gov/pubmed/21276430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.01.061
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