Programming the magnitude and persistence of antibody responses with innate immunity

Many successful vaccines induce persistent antibody responses that can last a lifetime. The mechanisms by which they do so remain unclear, but emerging evidence suggests that they activate dendritic cells (DCs) via Toll-like receptors (TLRs)1,2. For example, the yellow fever vaccine YF-17D, one of t...

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Main Authors: Kasturi, Sudhir Pai, Skountzou, Ioanna, Albrecht, Randy A., Koutsonanos, Dimitrios, Hua, Tang, Nakaya, Helder, Ravindran, Rajesh, Stewart, Shelley, Alam, Munir, Kwissa, Marcin, Villinger, Francois, Murthy, Niren, Steel, John, Jacob, Joshy, Hogan, Robert J., García-Sastre, Adolfo, Compans, Richard, Pulendran, Bali
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057367/
https://ncbi.nlm.nih.gov/pubmed/21350488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09737
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