The T helper type 2 response to cysteine proteases requires dendritic cell–basophil cooperation via ROS-mediated signaling

The mechanisms that initiate T helper type 2 (T(H)2) responses are poorly understood. Here we demonstrate that cysteine protease–induced T(H)2 responses occur via ‘cooperation’ between migratory dermal dendritic cells (DCs) and basophils positive for interleukin 4 (IL-4). Subcutaneous immunization w...

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Detalhes bibliográficos
Main Authors: Tang, Hua, Cao, Weiping, Kasturi, Sudhir Pai, Ravindran, Rajesh, Nakaya, Helder I, Kundu, Kousik, Murthy, Niren, Kepler, Thomas B, Malissen, Bernard, Pulendran, Bali
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145206/
https://ncbi.nlm.nih.gov/pubmed/20495560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1883
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