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Studying protein degradation pathways in vivo using a cranial window-based approach

Understanding how specific proteins are degraded by neurons in living animals is a fundamental question with relevance to many neurodegenerative diseases. Dysfunction in the ubiquitin-proteasome system (UPS) specifically has been implicated in several important neurodegenerative diseases including A...

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Huvudupphovsmän: Unni, Vivek K., Ebrahimi-Fakhari, Darius, Vanderburg, Charles R., McLean, Pamela J., Hyman, Bradley T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057351/
https://ncbi.nlm.nih.gov/pubmed/21187150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2010.12.032
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