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PROTEIN DEGRADATION PATHWAYS IN PARKINSON’S DISEASE – CURSE OR BLESSING

Protein misfolding, aggregation and deposition are common disease mechanisms in many neurodegenerative diseases including Parkinson’s disease. Accumulation of damaged or abnormally modified proteins may lead to perturbed cellular function and eventually to cell death. Thus neurons rely on elaborated...

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Detalhes bibliográficos
Main Authors: Ebrahimi-Fakhari, Darius, Wahlster, Lara, McLean, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417142/
https://ncbi.nlm.nih.gov/pubmed/22744791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1004-6
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