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PROTEIN DEGRADATION PATHWAYS IN PARKINSON’S DISEASE – CURSE OR BLESSING

Protein misfolding, aggregation and deposition are common disease mechanisms in many neurodegenerative diseases including Parkinson’s disease. Accumulation of damaged or abnormally modified proteins may lead to perturbed cellular function and eventually to cell death. Thus neurons rely on elaborated...

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Bibliografiske detaljer
Main Authors: Ebrahimi-Fakhari, Darius, Wahlster, Lara, McLean, Pamela J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417142/
https://ncbi.nlm.nih.gov/pubmed/22744791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1004-6
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