In Vivo Imaging of α-Synuclein in Mouse Cortex Demonstrates Stable Expression and Differential Subcellular Compartment Mobility

BACKGROUND: Regulation of α-synuclein levels within cells is thought to play a critical role in Parkinson's Disease (PD) pathogenesis and in other related synucleinopathies. These processes have been studied primarily in reduced preparations, including cell culture. We now develop methods to me...

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Bibliographic Details
Main Authors: Unni, Vivek K., Weissman, Tamily A., Rockenstein, Edward, Masliah, Eliezer, McLean, Pamela J., Hyman, Bradley T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868057/
https://ncbi.nlm.nih.gov/pubmed/20485674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010589
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