p190RhoGAP mediates protective effects of oxidized phospholipids in the models of ventilator induced lung injury

Products resulting from oxidation of cell membrane phospholipid 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) exhibit potent protective effects against lung endothelial cell (EC) barrier dysfunction caused by pathologically relevant mechanical forces and inflammatory agents. The...

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Main Authors: Birukova, Anna A., Zebda, Noureddine, Cokic, Ivan, Fu, Panfeng, Wu, Tinghuai, Dubrovskyi, Oleksii, Birukov, Konstantin G.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057230/
https://ncbi.nlm.nih.gov/pubmed/21111731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.11.011
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