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Characterizing the connectivity of poly-ubiquitin chains by selected reaction monitoring mass spectrometry

Protein ubiquitination is an essential post-translational modification (PTM) involved in the regulation of a variety of cellular functions, including transcription and protein degradation. Proteins can be both mono- or poly-ubiquitinated. Poly-ubiquitin chains vary in the manner by which the ubiquit...

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Detalhes bibliográficos
Main Authors: Mirzaei, Hamid, Rogers, Richard S., Grimes, Barbara, Eng, Jimmy, Aderem, Alan, Aebersold, Ruedi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057100/
https://ncbi.nlm.nih.gov/pubmed/20694217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c005242f
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