TGF-β Inducible Early Gene 1 Regulates Osteoclast Differentiation and Survival by Mediating the NFATc1, AKT, and MEK/ERK Signaling Pathways

TGF-β Inducible Early Gene-1 (TIEG1) is a Krüppel-like transcription factor (KLF10) that was originally cloned from human osteoblasts as an early response gene to TGF-β treatment. As reported previously, TIEG1(−/−) mice have decreased cortical bone thickness and vertebral bone volume and have increa...

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Autors principals: Cicek, Muzaffer, Vrabel, Anne, Sturchio, Catherine, Pederson, Larry, Hawse, John R., Subramaniam, Malayannan, Spelsberg, Thomas C., Oursler, Merry Jo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056664/
https://ncbi.nlm.nih.gov/pubmed/21423731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017522
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