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TGF-β Inducible Early Gene 1 Regulates Osteoclast Differentiation and Survival by Mediating the NFATc1, AKT, and MEK/ERK Signaling Pathways
TGF-β Inducible Early Gene-1 (TIEG1) is a Krüppel-like transcription factor (KLF10) that was originally cloned from human osteoblasts as an early response gene to TGF-β treatment. As reported previously, TIEG1(−/−) mice have decreased cortical bone thickness and vertebral bone volume and have increa...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Public Library of Science
2011
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056664/ https://ncbi.nlm.nih.gov/pubmed/21423731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017522 |
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