Blockade of osteopontin reduces alloreactive CD8(+) T cell–mediated graft-versus-host disease

Graft-versus-host disease (GVHD), a life-threatening complication after allogeneic hematopoietic stem cell transplantation, is caused by alloreactive donor T cells that trigger host tissue damage. The inflammatory environment inside recipients is critical for GVHD pathogenesis, but the underpinning...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhao, Fang, Zhang, Yi, Wang, Hao, Jin, Min, He, Shan, Shi, Yufang, Guo, Yajun, Zhang, Yanyun
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Transplantation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056597/
https://ncbi.nlm.nih.gov/pubmed/21119110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-281659
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