Allogeneic effector/memory Th-1 cells impair FoxP3(+) regulatory T lymphocytes and synergize with chaperone-rich cell lysate vaccine to treat leukemia

Therapeutic strategies combining the induction of effective antitumor immunity with the inhibition of the mechanisms of tumor-induced immunosuppression represent a key objective in cancer immunotherapy. Herein we demonstrate that effector/memory CD4(+) T helper-1 (Th-1) lymphocytes, in addition to p...

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Detalhes bibliográficos
Main Authors: Janikashvili, Nona, LaCasse, Collin J., Larmonier, Claire, Trad, Malika, Herrell, Amanda, Bustamante, Sara, Bonnotte, Bernard, Har-Noy, Michael, Larmonier, Nicolas, Katsanis, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056591/
https://ncbi.nlm.nih.gov/pubmed/21123824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-288621
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