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Farnesoid X receptor antagonizes NF-κB in hepatic inflammatory response

The farnesoid X receptor (FXR) is a nuclear receptor that plays key roles in hepatoprotection by maintaining the homeostasis of liver metabolism. FXR null mice display strong hepatic inflammation and develop spontaneous liver tumors. In this report, we demonstrate that FXR is a negative modulator of...

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Bibliografski detalji
Glavni autori: Wang, Yan-Dong, Chen, Wei-Dong, Wang, Meihua, Yu, Donna, Forman, Barry M., Huang, Wendong
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056574/
https://ncbi.nlm.nih.gov/pubmed/18972444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22519
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