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Farnesoid X receptor antagonizes NF-κB in hepatic inflammatory response
The farnesoid X receptor (FXR) is a nuclear receptor that plays key roles in hepatoprotection by maintaining the homeostasis of liver metabolism. FXR null mice display strong hepatic inflammation and develop spontaneous liver tumors. In this report, we demonstrate that FXR is a negative modulator of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056574/ https://ncbi.nlm.nih.gov/pubmed/18972444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22519 |
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