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Dose-Levels and First Signs of Efficacy in Contemporary Oncology Phase 1 Clinical Trials

PURPOSE: Phase 1 trials play a crucial role in oncology by translating laboratory science into efficient therapies. Molecular targeted agents (MTA) differ from traditional cytotoxics in terms of both efficacy and toxicity profiles. Recent reports suggest that higher doses are not essential to produc...

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Sonraí Bibleagrafaíochta
Main Authors: Ferte, Charles, Soria, Jean-Charles, Penel, Nicolas
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056556/
https://ncbi.nlm.nih.gov/pubmed/21415927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016633
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