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Dose-Levels and First Signs of Efficacy in Contemporary Oncology Phase 1 Clinical Trials
PURPOSE: Phase 1 trials play a crucial role in oncology by translating laboratory science into efficient therapies. Molecular targeted agents (MTA) differ from traditional cytotoxics in terms of both efficacy and toxicity profiles. Recent reports suggest that higher doses are not essential to produc...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056556/ https://ncbi.nlm.nih.gov/pubmed/21415927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016633 |
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