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Dose-Levels and First Signs of Efficacy in Contemporary Oncology Phase 1 Clinical Trials

PURPOSE: Phase 1 trials play a crucial role in oncology by translating laboratory science into efficient therapies. Molecular targeted agents (MTA) differ from traditional cytotoxics in terms of both efficacy and toxicity profiles. Recent reports suggest that higher doses are not essential to produc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ferte, Charles, Soria, Jean-Charles, Penel, Nicolas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056556/
https://ncbi.nlm.nih.gov/pubmed/21415927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016633
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