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Functional interaction between RAFT1/FRAP/mTOR and protein kinase Cδ in the regulation of cap-dependent initiation of translation

Hormones and growth factors induce protein translation in part by phosphorylation of the eukaryotic initiation factor 4E (eIF4E) binding protein 1 (4E-BP1). The rapamycin and FK506-binding protein (FKBP)-target 1 (RAFT1, also known as FRAP) is a mammalian homolog of the Saccharomyces cerevisiae targ...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Kumar, Vijay, Pandey, Pramod, Sabatini, David, Kumar, Madhur, Majumder, Pradip K., Bharti, Ajit, Carmichael, Gordon, Kufe, Donald, Kharbanda, Surender
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10698949/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.5.1087
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