Phase I Trial of Lenalidomide in Pediatric Patients With Recurrent, Refractory, or Progressive Primary CNS Tumors: Pediatric Brain Tumor Consortium Study PBTC-018

PURPOSE: A phase I trial of lenalidomide was performed in children with recurrent, refractory, or progressive primary CNS tumors to estimate the maximum-tolerated dose (MTD) and to describe the toxicity profile and pharmacokinetics. PATIENTS AND METHODS: Lenalidomide was administered by mouth daily...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Warren, Katherine E., Goldman, Stewart, Pollack, Ian F., Fangusaro, Jason, Schaiquevich, Paula, Stewart, Clinton F., Wallace, Dana, Blaney, Susan M., Packer, Roger, MacDonald, Tobey, Jakacki, Regina, Boyett, James M., Kun, Larry E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Clinical Oncology 2011
Θέματα:
Original Reports
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056466/
https://ncbi.nlm.nih.gov/pubmed/21149652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.31.3601
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