Phase I Trial of Lenalidomide in Pediatric Patients With Recurrent, Refractory, or Progressive Primary CNS Tumors: Pediatric Brain Tumor Consortium Study PBTC-018

PURPOSE: A phase I trial of lenalidomide was performed in children with recurrent, refractory, or progressive primary CNS tumors to estimate the maximum-tolerated dose (MTD) and to describe the toxicity profile and pharmacokinetics. PATIENTS AND METHODS: Lenalidomide was administered by mouth daily...

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Hlavní autoři: Warren, Katherine E., Goldman, Stewart, Pollack, Ian F., Fangusaro, Jason, Schaiquevich, Paula, Stewart, Clinton F., Wallace, Dana, Blaney, Susan M., Packer, Roger, MacDonald, Tobey, Jakacki, Regina, Boyett, James M., Kun, Larry E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2011
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056466/
https://ncbi.nlm.nih.gov/pubmed/21149652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.31.3601
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