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Synthesis of (±)-7-Hydroxylycopodine
[Image: see text] A 6 step synthesis of (±)-7-hydroxylycopodine has been achieved in 5% overall yield. In the key step, a Prins cyclization of a bicyclic keto alkyne in 60% H(2)SO(4) forms a tricyclic dihydroxy amino ketone.
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056437/ https://ncbi.nlm.nih.gov/pubmed/21271726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol200119h |
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