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Structure of the RXR–RAR DNA-binding complex on the retinoic acid response element DR1

The 9–cis retinoic acid receptor (retinoid X receptor, RXR) forms heterodimers with the all-trans retinoic acid receptor (RAR) and other nuclear receptors on DNA regulatory sites composed of tandem binding elements. We describe the 1.70 Å resolution structure of the ternary complex of RXR and RAR DN...

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Autors principals: Rastinejad, Fraydoon, Wagner, Trixie, Zhao, Qiang, Khorasanizadeh, Sepideh
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC305643/
https://ncbi.nlm.nih.gov/pubmed/10698945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.5.1045
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