Palmitate-induced skeletal muscle insulin resistance does not require NF-κB activation

Palmitate activates the NF-κB pathway, and induces accumulation of lipid metabolites and insulin resistance in skeletal muscle cells. Little information is available whether and how these processes are causally related. Therefore, the objectives were to investigate whether intra-cellular lipid metab...

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Autori principali: Hommelberg, Pascal P. H., Plat, Jogchum, Sparks, Lauren M., Schols, Annemie M. W. J., van Essen, Anon L. M., Kelders, Marco C. J. M., van Beurden, Denis, Mensink, Ronald P., Langen, Ramon C. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: SP Birkhäuser Verlag Basel 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056136/
https://ncbi.nlm.nih.gov/pubmed/20820848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0515-3
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