Pulmonary inflammation-induced loss and subsequent recovery of skeletal muscle mass require functional poly-ubiquitin conjugation

BACKGROUND: Pulmonary inflammation in response to respiratory infections can evoke muscle wasting. Increased activity of the ubiquitin (Ub)-proteasome system (UPS) and the autophagy lysosome pathway (ALP) have been implicated in inflammation-induced muscle atrophy. Since poly-Ub conjugation is requi...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Ceelen, Judith J. M., Schols, Annemie M. W. J., Thielen, Nathalie G. M., Haegens, Astrid, Gray, Douglas A., Kelders, Marco C. J. M., de Theije, Chiel C., Langen, Ramon C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932886/
https://ncbi.nlm.nih.gov/pubmed/29720191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0753-8
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