Pulmonary inflammation-induced loss and subsequent recovery of skeletal muscle mass require functional poly-ubiquitin conjugation

BACKGROUND: Pulmonary inflammation in response to respiratory infections can evoke muscle wasting. Increased activity of the ubiquitin (Ub)-proteasome system (UPS) and the autophagy lysosome pathway (ALP) have been implicated in inflammation-induced muscle atrophy. Since poly-Ub conjugation is requi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Respir Res
Prif Awduron: Ceelen, Judith J. M., Schols, Annemie M. W. J., Thielen, Nathalie G. M., Haegens, Astrid, Gray, Douglas A., Kelders, Marco C. J. M., de Theije, Chiel C., Langen, Ramon C. J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932886/
https://ncbi.nlm.nih.gov/pubmed/29720191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0753-8
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