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Op18/stathmin caps a kinked protofilament-like tubulin tetramer
Oncoprotein 18/stathmin (Op18), a regulator of microtubule dynamics, was recombinantly expressed and its structure and function analysed. We report that Op18 by itself can fold into a flexible and extended α-helix, which is in equilibrium with a less ordered structure. In complex with tubulin, howev...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305595/ https://ncbi.nlm.nih.gov/pubmed/10675326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.572 |
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