Op18/Stathmin Mediates Multiple Region-Specific Tubulin and Microtubule-Regulating Activities

Oncoprotein18/stathmin (Op18) is a regulator of microtubule (MT) dynamics that binds tubulin heterodimers and destabilizes MTs by promoting catastrophes (i.e., transitions from growing to shrinking MTs). Here, we have performed a deletion analysis to mechanistically dissect Op18 with respect to (a)...

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Autores principales: Larsson, Niklas, Segerman, Bo, Howell, Bonnie, Fridell, Kajsa, Cassimeris, Lynne, Gullberg, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1999
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156119/
https://ncbi.nlm.nih.gov/pubmed/10491392
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