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Adjunctive Dexamethasone Affects the Expression of Genes Related to Inflammation, Neurogenesis and Apoptosis in Infant Rat Pneumococcal Meningitis

Streptococcus pneumoniae is the most common pathogen causing non-epidemic bacterial meningitis worldwide. The immune response and inflammatory processes contribute to the pathophysiology. Hence, the anti-inflammatory dexamethasone is advocated as adjuvant treatment although its clinical efficacy rem...

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Détails bibliographiques
Auteurs principaux: Blaser, Cornelia, Wittwer, Matthias, Grandgirard, Denis, Leib, Stephen L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055894/
https://ncbi.nlm.nih.gov/pubmed/21412436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017840
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