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Tracking the transcriptional host response from the acute to the regenerative phase of experimental pneumococcal meningitis

BACKGROUND: Despite the availability of effective antibiotic therapies, pneumococcal meningitis (PM) has a case fatality rate of up to 30% and causes neurological sequelae in up to half of the surviving patients. The underlying brain damage includes apoptosis of neurons in the hippocampus and necros...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wittwer, Matthias, Grandgirard, Denis, Rohrbach, Janine, Leib, Stephen L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915993/
https://ncbi.nlm.nih.gov/pubmed/20565785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-10-176
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