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Excess histone levels mediate cytotoxicity via multiple mechanisms

The accumulation of excess histone proteins in cells has deleterious consequences such as genomic instability in the form of excessive chromosome loss, enhanced sensitivity to DNA damaging agents and cytotoxicity. Hence, the synthesis of histone proteins is tightly regulated at multiple steps and tr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Singh, Rakesh Kumar, Liang, Dun, Gajjalaiahvari, Ugander Reddy, Kabbaj, Marie-Helene Miquel, Paik, Johanna, Gunjan, Akash
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055206/
https://ncbi.nlm.nih.gov/pubmed/20948314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13636
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