FACT Prevents the Accumulation of Free Histones Evicted from Transcribed Chromatin and a Subsequent Cell Cycle Delay in G1

The FACT complex participates in chromatin assembly and disassembly during transcription elongation. The yeast mutants affected in the SPT16 gene, which encodes one of the FACT subunits, alter the expression of G1 cyclins and exhibit defects in the G1/S transition. Here we show that the dysfunction...

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Hauptverfasser: Morillo-Huesca, Macarena, Maya, Douglas, Muñoz-Centeno, Mari Cruz, Singh, Rakesh Kumar, Oreal, Vincent, Reddy, Gajjalaiahvari Ugander, Liang, Dun, Géli, Vincent, Gunjan, Akash, Chávez, Sebastián
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873916/
https://ncbi.nlm.nih.gov/pubmed/20502685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000964
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