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Reduced spermatogonial proliferation and decreased fertility in mice overexpressing cyclin E in spermatogonia
Cyclin E is a key component of the cell cycle regulatory machinery, contributing to the activation of Cdk2 and the control of cell cycle progression at several stages. Cyclin E expression is tightly regulated, by periodic transcription and ubiquitin-mediated degradation. Overexpression of cyclin E h...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3055205/ https://ncbi.nlm.nih.gov/pubmed/20962587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13544 |
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