Potentials and limitations of adenovirus-p53 gene therapy for brain tumors.

We investigated the antineoplastic potentials of recombinant adenovirus containing wild-type p53 cDNA (Ad5CMV-p53) for malignant gliomas. In four human glioma cell lines (U-251 and LG expressing endogenous mutant p53, and U-87 and EFC-2 expressing wild-type p53) and two rat glioma cell lines (9L and...

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Bibliographic Details
Main Authors: Hong, Y. K., Joe, Y. A., Yang, Y. J., Lee, K. S., Son, B. C., Jeun, S. S., Chung, D. S., Cho, K. K., Park, C. K., Kim, M. C., Kim, H. K., Yung, W. K., Kang, J. K.
Format: Artigo
Language:Inglês
Published: Korean Academy of Medical Sciences 2000
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3054646/
https://ncbi.nlm.nih.gov/pubmed/10895975
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