Inhibition of breast cancer growth in vivo by antiangiogenesis gene therapy with adenovirus-mediated antisense-VEGF

Increased expression of VEGF in several types of tumours has been shown to correlate with poor prognosis. We used a replication-deficient adenoviral vector containing antisense VEGF cDNA (Ad5CMV-αVEGF) to down-regulate VEGF expression and increase the efficiency of delivery of the antisense sequence...

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Detalhes bibliográficos
Main Authors: Im, S-A, Kim, J-S, Gomez-Manzano, C, Fueyo, J, Liu, T-J, Cho, M-S, Seong, C-M, Lee, S N, Hong, Y-K, Yung, W K A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363890/
https://ncbi.nlm.nih.gov/pubmed/11336478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1734
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