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Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency

Claudins (Clds) are crucial constituents of tight-junction strands in epithelial cells and have a central role in barrier functions. We show that Cld4 is unexpectedly expressed in normal thymic lymphocytes independently of tight junctions. The Cld4 expression was mostly confined to a portion of the...

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Bibliographische Detailangaben
Hauptverfasser: Kawai, Yohei, Hamazaki, Yoko, Fujita, Harumi, Fujita, Akikazu, Sato, Takehito, Furuse, Mikio, Fujimoto, Toyoshi, Jetten, Anton M., Agata, Yasutoshi, Minato, Nagahiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3054041/
https://ncbi.nlm.nih.gov/pubmed/21325057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014178108
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