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Claudin-4 Deficiency Results in Urothelial Hyperplasia and Lethal Hydronephrosis

Claudin (Cld)-4 is one of the dominant Clds expressed in the kidney and urinary tract, including selective segments of renal nephrons and the entire urothelium from the pelvis to the bladder. We generated Cldn4 (−/−) mice and found that these mice had increased mortality due to hydronephrosis of rel...

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Bibliografiske detaljer
Main Authors: Fujita, Harumi, Hamazaki, Yoko, Noda, Yumi, Oshima, Masanobu, Minato, Nagahiro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528782/
https://ncbi.nlm.nih.gov/pubmed/23284964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052272
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