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Claudin-4 Deficiency Results in Urothelial Hyperplasia and Lethal Hydronephrosis

Claudin (Cld)-4 is one of the dominant Clds expressed in the kidney and urinary tract, including selective segments of renal nephrons and the entire urothelium from the pelvis to the bladder. We generated Cldn4 (−/−) mice and found that these mice had increased mortality due to hydronephrosis of rel...

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Detalhes bibliográficos
Main Authors: Fujita, Harumi, Hamazaki, Yoko, Noda, Yumi, Oshima, Masanobu, Minato, Nagahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528782/
https://ncbi.nlm.nih.gov/pubmed/23284964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052272
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