Expression, signaling proficiency, and stimulatory function of the NKG2D lymphocyte receptor in human cancer cells

The stimulatory natural killer group 2 member D (NKG2D) lymphocyte receptor and its tumor-associated ligands are important mediators in the immune surveillance of cancer. With advanced human tumors, however, persistent NKG2D ligand expression may favor tumor progression. We have found that cancer ce...

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Autori principali: Benitez, Andrea Caballero, Dai, Zhenpeng, Mann, Henning H., Reeves, Rebecca S., Margineantu, Daciana H., Gooley, Ted A., Groh, Veronika, Spies, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3054013/
https://ncbi.nlm.nih.gov/pubmed/21321202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018603108
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