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Normally occurring NKG2D(+)CD4(+) T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus
The NKG2D receptor stimulates natural killer cell and T cell responses upon engagement of ligands associated with malignancies and certain autoimmune diseases. However, conditions of persistent NKG2D ligand expression can lead to immunosuppression. In cancer patients, tumor expression and shedding o...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715116/ https://ncbi.nlm.nih.gov/pubmed/19289577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081648 |
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