Autonomous Stimulation of Cancer Cell Plasticity by the Human NKG2D Lymphocyte Receptor Coexpressed with Its Ligands on Cancer Cells

The stimulatory NKG2D receptor on lymphocytes promotes tumor immune surveillance by targeting ligands selectively induced on cancer cells. Progressing tumors counteract by employing tactics to disable lymphocyte NKG2D. This negative dynamic is escalated as some human cancer cells co-opt expression o...

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Detalhes bibliográficos
Main Authors: Cai, Xin, Dai, Zhenpeng, Reeves, Rebecca S., Caballero-Benitez, Andrea, Duran, Kate L., Delrow, Jeffrey J., Porter, Peggy L., Spies, Thomas, Groh, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188595/
https://ncbi.nlm.nih.gov/pubmed/25291178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108942
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