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Autonomous Stimulation of Cancer Cell Plasticity by the Human NKG2D Lymphocyte Receptor Coexpressed with Its Ligands on Cancer Cells

The stimulatory NKG2D receptor on lymphocytes promotes tumor immune surveillance by targeting ligands selectively induced on cancer cells. Progressing tumors counteract by employing tactics to disable lymphocyte NKG2D. This negative dynamic is escalated as some human cancer cells co-opt expression o...

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Bibliografiska uppgifter
Huvudupphovsmän: Cai, Xin, Dai, Zhenpeng, Reeves, Rebecca S., Caballero-Benitez, Andrea, Duran, Kate L., Delrow, Jeffrey J., Porter, Peggy L., Spies, Thomas, Groh, Veronika
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188595/
https://ncbi.nlm.nih.gov/pubmed/25291178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108942
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