C-terminal-truncated apolipoprotein (apo) E4 inefficiently clears amyloid-β (Aβ) and acts in concert with Aβ to elicit neuronal and behavioral deficits in mice

Eitemau Tebyg

• Apolipoprotein E4 Causes Age- and Tau-Dependent Impairment of GABAergic Interneurons, Leading to Learning and Memory Deficits in Mice
  gan: Andrews-Zwilling, Yaisa, et al.
  Cyhoeddwyd: (2010)
• GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knock-in Mice
  gan: Li, Gang, et al.
  Cyhoeddwyd: (2009)
• Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent Aβ Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice
  gan: Bien-Ly, Nga, et al.
  Cyhoeddwyd: (2012)
• Profile and Regulation of Apolipoprotein E (ApoE) Expression in the CNS in Mice with Targeting of Green Fluorescent Protein Gene to the ApoE Locus
  gan: Xu, Qin, et al.
  Cyhoeddwyd: (2006)
• Lipoproteins containing the truncated apolipoprotein, Apo B-89, are cleared from human plasma more rapidly than Apo B-100-containing lipoproteins in vivo.
  gan: Parhofer, K G, et al.
  Cyhoeddwyd: (1992)