Loss of retinoblastoma gene and amplification of N-myc gene in retinoblastoma.

We have analyzed paired samples of genomic DNA from peripheral leukocyte and primary tumor tissue from nine patients with retinoblastoma (RB) and from two RB cell lines, WERI-Rb-1 and Y79, to detect the molecular alterations of the retinoblastoma susceptibility gene (RB-1) and N-myc gene. In Souther...

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Main Authors: Choi, S. W., Lee, T. W., Yang, S. W., Hong, W. S., Kim, C. M., Lee, J. O.
Format: Artigo
Sprog:Inglês
Udgivet: Korean Academy of Medical Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053849/
https://ncbi.nlm.nih.gov/pubmed/8343223
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