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Detection of N-myc gene amplification by fluorescence in situ hybridization. Diagnostic utility for neuroblastoma.

We assessed fluorescence in situ hybridization (FISH) as an alternative to Southern blot analysis for determination of N-myc gene amplification in neuroblastoma. In the 44 pediatric solid tumor cell lines examined (20 neuroblastomas), the mean number of N-myc copies determined by FISH correlated clo...

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Hlavní autoři: Shapiro, D. N., Valentine, M. B., Rowe, S. T., Sinclair, A. E., Sublett, J. E., Roberts, W. M., Look, A. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886925/
https://ncbi.nlm.nih.gov/pubmed/7684192
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