Detection of N-myc gene amplification by fluorescence in situ hybridization. Diagnostic utility for neuroblastoma.

We assessed fluorescence in situ hybridization (FISH) as an alternative to Southern blot analysis for determination of N-myc gene amplification in neuroblastoma. In the 44 pediatric solid tumor cell lines examined (20 neuroblastomas), the mean number of N-myc copies determined by FISH correlated clo...

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Main Authors: Shapiro, D. N., Valentine, M. B., Rowe, S. T., Sinclair, A. E., Sublett, J. E., Roberts, W. M., Look, A. T.
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886925/
https://ncbi.nlm.nih.gov/pubmed/7684192
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